演員表
- 導演：
- 編劇：
- 演員：
- 強尼葛萊奇 Johnny Galecki ............Leonard Hofstadter 264 episodes, 2006-2018
- 吉姆帕森斯 Jim Parsons ............Sheldon Cooper 264 episodes, 2006-2018
- 卡蕾庫奧科 Kaley Cuoco ............Penny 263 episodes, 2007-2018
- 賽門海柏格 Simon Helberg ............Howard Wolowitz 263 episodes, 2007-2018
- 昆瑙納亞爾 Kunal Nayyar ............Raj Koothrappali 263 episodes, 2007-2018
- 梅麗莎勞奇 Melissa Rauch ............Bernadette Rostenkowski 193 episodes, 2009-2018
- Mayim Bialik ............Amy Farrah Fowler 187 episodes, 2010-2018
- Kevin Sussman ............Stuart Bloom 74 episodes, 2009-2018
- Carol Ann Susi ............Debbie Wolowitz 40 episodes, 2007-2017
- John Ross Bowie ............Barry Kripke 22 episodes, 2009-2018
- Laura Spencer ............Emily Sweeney 17 episodes, 2014-2017
- Wil Wheaton ............Wil Wheaton 16 episodes, 2009-2018
- Brian George ............Dr. V.M. Koothrappali 15 episodes, 2007-2018
- 蘿莉麥卡佛 Laurie Metcalf ............Mary Cooper 14 episodes, 2007-2018
- 克莉絲汀巴倫絲基 Christine Baranski ............Dr. Beverly Hofstadter 13 episodes, 2009-2018
